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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
13.64
Human Site:
S348
Identified Species:
23.08
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
S348
F
G
A
R
D
A
A
S
Q
E
P
K
Y
Q
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S351
F
G
A
R
D
A
A
S
Q
E
P
K
Y
Q
L
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
S351
F
G
A
R
D
A
A
S
Q
E
P
K
Y
Q
L
Dog
Lupus familis
XP_538827
1042
119346
S349
F
G
A
R
D
A
A
S
Q
E
P
K
Y
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
D442
L
S
K
E
E
F
P
D
F
D
E
E
T
G
I
Rat
Rattus norvegicus
NP_997661
1044
119245
A350
F
G
A
R
D
A
A
A
Q
E
P
Q
Y
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
A338
W
P
C
P
M
T
F
A
A
K
G
R
R
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
E361
R
R
I
K
E
E
Q
E
R
Y
Q
L
I
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
I272
V
K
E
H
Q
V
L
I
I
E
G
E
T
G
S
Honey Bee
Apis mellifera
XP_001122325
831
95330
E209
D
H
Q
V
L
I
I
E
G
E
T
G
S
G
K
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
R317
L
G
A
K
D
A
K
R
K
E
Q
E
F
E
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
L433
A
A
A
L
Q
S
A
L
T
K
E
R
R
E
M
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
D432
I
R
K
Q
Q
S
F
D
D
P
T
K
N
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
100
100
100
N.A.
0
86.6
N.A.
N.A.
0
N.A.
0
N.A.
6.6
6.6
40
0
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
N.A.
40
N.A.
20
N.A.
13.3
6.6
73.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
50
0
0
43
43
15
8
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
43
0
0
15
8
8
0
0
0
0
0
% D
% Glu:
0
0
8
8
15
8
0
15
0
58
15
22
0
15
8
% E
% Phe:
36
0
0
0
0
8
15
0
8
0
0
0
8
0
0
% F
% Gly:
0
43
0
0
0
0
0
0
8
0
15
8
0
22
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
8
8
8
0
0
0
8
0
8
% I
% Lys:
0
8
15
15
0
0
8
0
8
15
0
36
0
15
15
% K
% Leu:
15
0
0
8
8
0
8
8
0
0
0
8
0
8
43
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
8
0
0
8
0
0
8
36
0
0
0
0
% P
% Gln:
0
0
8
8
22
0
8
0
36
0
15
8
0
36
0
% Q
% Arg:
8
15
0
36
0
0
0
8
8
0
0
15
15
0
0
% R
% Ser:
0
8
0
0
0
15
0
29
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
15
0
15
0
0
% T
% Val:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
36
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _